Description

1-Propanone, 1-(4-Methyl-2-Piperazinyl)- is a specialized organic compound featuring a ketone group linked to a substituted piperazine moiety. This unique molecular architecture makes it a valuable key intermediate in the synthesis of complex pharmacologically active molecules. It is primarily utilized by pharmaceutical research and development organizations and fine chemical manufacturers requiring high-purity building blocks.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals and advanced material science applications.
• Biochemical Research: May be utilized as a reagent or ligand in biochemical assays and proteomics research due to its potential for specific molecular interactions.

Basic Information

Product Name	1-Propanone, 1-(4-Methyl-2-Piperazinyl)-
CAS No.	224189-09-7
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	1-(4-Methylpiperazin-2-yl)propan-1-one; 4-Methyl-2-propionylpiperazine; 1-Propanone,1-(4-methyl-2-piperazinyl)-; 2-Propionyl-4-methylpiperazine; 4-Methyl-2-propionylpiperazine; 1-(4-Methyl-2-piperazinyl)-1-propanone
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 1-(4-Methyl-2-Piperazinyl)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.