Description

4-(4-Bromophenyl)-3,6-Dihydro-2H-Pyran is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a reactive handle for cross-coupling reactions and serves as a key precursor for constructing complex molecular architectures. Pharmaceutical, agrochemical, and material science researchers need it for developing new active ingredients and functional molecules, leveraging its unique dihydropyran scaffold fused with an aryl bromide moiety.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the bromophenyl group can be further functionalized.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, aromatic structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical and cellular studies.

Basic Information

Product Name	4-(4-Bromophenyl)-3,6-Dihydro-2H-Pyran
CAS No.	223555-87-1
Molecular Formula	C11H11BrO
Molecular Weight	239.11 g/mol
Synonyms	4-(4-Bromophenyl)-3,6-dihydro-2H-pyran; 2H-Pyran, 3,6-dihydro-4-(4-bromophenyl)-; 4-(p-Bromophenyl)-3,6-dihydro-2H-pyran; 3,6-Dihydro-4-(4-bromophenyl)-2H-pyran; 4-(4-Bromophenyl)-3,6-dihydro-2H-pyran (CAS 223555-87-1); 4-(4-Bromophenyl)-3,6-dihydropyran
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Bromophenyl)-3,6-Dihydro-2H-Pyran undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. Our quality management system is designed to provide full traceability and reliability for your synthetic workflows. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.