Description

6-Bromo-7-Hydroxy-4-(Hydroxymethyl)-2H-Chromen-2-One is a high-purity, functionalized coumarin derivative serving as a critical advanced intermediate in organic synthesis. Its unique bromo-hydroxy substitution pattern makes it a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and R&D laboratories focused on developing novel active pharmaceutical ingredients (APIs), fluorescent probes, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or possessing fluorescent properties for bio-imaging.
• Fluorescent Probe Development: Serves as a core scaffold for creating sensitive and selective fluorescent sensors and markers used in biochemical assays and diagnostic applications.
• Organic Light-Emitting Diode (OLED) Materials: Used in research for developing new electron-transport or emissive layer materials due to the coumarin core's photophysical properties.
• Agrochemical Research: Intermediate for synthesizing new compounds with potential herbicidal or pesticidal activity.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reactions, heterocyclic chemistry, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Building block for specialty chemicals used in dyes, pigments, and other performance materials.

Basic Information

Product Name	6-Bromo-7-Hydroxy-4-(Hydroxymethyl)-2H-Chromen-2-One
CAS No.	223420-41-5
Molecular Formula	C10H7BrO4
Molecular Weight	271.07 g/mol
Synonyms	6-Bromo-7-hydroxy-4-(hydroxymethyl)-2H-1-benzopyran-2-one; 4-(Hydroxymethyl)-6-bromo-7-hydroxycoumarin; 6-Bromo-7-hydroxy-4-hydroxymethylcoumarin; 7-Hydroxy-6-bromo-4-hydroxymethylcoumarin; BHHC; Coumarin derivative, bromo-hydroxy substituted; 223420-41-5; Contact for EINECS details.

Quality Control

Every batch of 6-Bromo-7-Hydroxy-4-(Hydroxymethyl)-2H-Chromen-2-One is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), is performed. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.