Description

Denatonium Hydroxide is a high-purity quaternary ammonium salt renowned as one of the most intensely bitter-tasting substances known. This property makes it an exceptionally effective and versatile denaturant and aversive agent for a wide range of industrial and consumer products. It is a critical additive for manufacturers requiring reliable, safe, and compliant bitterness to prevent accidental or intentional ingestion. Key industries that utilize this compound include pharmaceuticals, personal care, household chemicals, and industrial fluids.

Application

• Alcohol Denaturant: Primary use in rendering ethanol and other alcohols unfit for human consumption in industrial solvents, fuels, and cleaning products.
• Pharmaceutical Safety Agent: Incorporated into topical medications, nail-biting preventatives, and oral liquid formulations to deter accidental ingestion, especially by children.
• Personal Care & Cosmetics: Added to products like nail polish removers, shampoos, and cosmetics to prevent oral consumption.
• Household & Automotive Chemicals: Used in antifreeze, windshield washer fluids, detergents, and disinfectants as a safety measure against poisoning.
• Animal Repellents: Applied in animal deterrent sprays to protect gardens, crops, and property from pests like rodents and deer.
• Industrial Additive: Serves as a bittering agent in specialty paints, coatings, and plastics to discourage chewing or licking.

Basic Information

Product Name	Denatonium Hydroxide
CAS No.	222608-06-2
Molecular Formula	C21H29N2O2
Molecular Weight	341.47 g/mol
Synonyms	Denatonium Hydroxide; Denatonium Benzoate Hydroxide; Benzyldiethyl[(2,6-xylylcarbamoyl)methyl]ammonium Hydroxide; Lidocaine Benzyl Benzoate Hydroxide; Bitrex® (Trade Name); THS-839; Aversion Agent B; Bittering Agent 222608-06-2
EINECS	Contact for details

Quality Control

Our Denatonium Hydroxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding applications. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, identification, and impurity profiles. While not a pharmacopoeial substance, production can be aligned with cGMP principles for relevant applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.