Description

R-Equol CAS NO 221054-79-1 is a high-purity, enantiomerically pure form of the soy isoflavone metabolite equol, specifically the (R)-enantiomer. This compound is of significant commercial and research interest due to its potent and selective estrogenic activity, particularly its high affinity for estrogen receptor beta (ERβ). It is primarily sought by manufacturers and researchers in the nutraceutical, pharmaceutical, and life science sectors for developing advanced health supplements and therapeutic agents targeting hormone-related conditions.

Application

• Nutraceutical Formulations: A key bioactive ingredient in dietary supplements for menopausal health, bone density support, and antioxidant benefits.
• Pharmaceutical Intermediates: Serves as a critical chiral building block or active pharmaceutical ingredient (API) in the development of selective estrogen receptor modulators (SERMs).
• Clinical & Preclinical Research: Used as a reference standard and investigational compound in studies related to endocrinology, oncology, and cardiovascular health.
• Cosmeceuticals: Incorporated into skincare products for its potential anti-aging and skin-protective properties linked to estrogenic pathways.
• Functional Food & Beverage Fortification: Enhances the health profile of foods designed for specific wellness outcomes.
• Veterinary Health Products: Applied in supplements for managing hormonal balance and supporting joint health in animals.

Basic Information

Product Name	R-Equol
CAS No.	221054-79-1
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	(R)-Equol; (3R)-3-(4-Hydroxyphenyl)-7-chromanol; 7-Hydroxy-3-(4-hydroxyphenyl)-chroman; (-)-Equol; S-Equol (enantiomer); Equol (R-enantiomer); Soy Isoflavone Metabolite
EINECS	Contact for details

Quality Control

Our R-Equol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for identity, potency, and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP principles where applicable to support its use in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (R-enantiomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.