Description

5-Bromo-2-Fluorostyrene is a versatile halogenated styrene derivative, a key building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, which allows for selective functionalization and the introduction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, serving as a critical intermediate for the development of active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, enhancing thermal stability and optoelectronic properties.
• Polymer & Resin Modification: Incorporated as a functional monomer to introduce bromine and fluorine into polymer backbones, improving flame retardancy and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	5-Bromo-2-Fluorostyrene
CAS No.	221030-92-8
Molecular Formula	C8H6BrF
Molecular Weight	201.04 g/mol
Synonyms	2-Fluoro-5-bromostyrene; 1-Bromo-4-ethenyl-2-fluorobenzene; (2-Fluoro-5-bromophenyl)ethene; 5-Bromo-2-fluorostyrol; 5-Bromo-2-fluorophenylethene; 221030-92-8; 5-Br-2-F-styrene
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Fluorostyrene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.