Description

2-(4-Fluorfenyl)-4-(3-Hydroxy-3-Methylbutoxy)-5-(4-Mesylfenyl)Pyridazine-3(2H)-On is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Biochemical Research: Used in the development of enzyme inhibitors and receptor modulators for preclinical studies.
• Organic Synthesis: Serves as a versatile precursor for constructing complex pyridazine-based molecular scaffolds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for medicinal chemistry and heterocyclic chemistry studies.

Basic Information

Product Name	2-(4-Fluorfenyl)-4-(3-Hydroxy-3-Methylbutoxy)-5-(4-Mesylfenyl)Pyridazine-3(2H)-On
CAS No.	221030-56-4
Molecular Formula	C22H21FN2O5S
Molecular Weight	444.48 g/mol
Synonyms	2-(4-Fluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one; 5-(4-Methanesulfonylphenyl)-2-(4-fluorophenyl)-4-(3-hydroxy-3-methylbutoxy)pyridazin-3(2H)-one; 221030-56-4; 2-(4-Fluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-[4-(methylsulfonyl)phenyl]-2,3-dihydropyridazin-3-one; 5-(4-Mesylphenyl)-2-(4-fluorophenyl)-4-(3-hydroxy-3-methylbutoxy)pyridazin-3(2H)-one
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorfenyl)-4-(3-Hydroxy-3-Methylbutoxy)-5-(4-Mesylfenyl)Pyridazine-3(2H)-On is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch, and we support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.