Description

4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile, 2-Amino-4-(2-Chlorophenyl)-7-Methyl-5-Oxo- is a high-value, heterocyclic organic compound with a complex fused pyranopyran structure, serving as a critical synthetic intermediate. Its molecular architecture, featuring a nitrile group, an amino group, and a chlorophenyl substituent, makes it a versatile building block for constructing more complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive chemical space.
• Agrochemical Development: Potential intermediate in the research and development of new active ingredients for crop protection products.
• Advanced Material Synthesis: May be utilized in the creation of specialized organic materials, such as ligands for catalysis or components for organic electronics, due to its rigid, conjugated structure.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile, 2-Amino-4-(2-Chlorophenyl)-7-Methyl-5-Oxo-
CAS No.	220986-34-5
Molecular Formula	C16H13ClN2O2
Molecular Weight	300.74 g/mol
Synonyms	2-Amino-4-(2-chlorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(2-chlorophenyl)-7-methyl-5-oxo-; 2-Amino-4-(2-chlorophenyl)-7-methyl-5-oxopyrano[4,3-b]pyran-3-carbonitrile; 220986-34-5; 4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(2-chlorophenyl)-7-methyl-5-oxo-; 2-Amino-4-(2-chlorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(2-chlorophenyl)-7-methyl-5-oxo- (ACI); AKOS BRN-0715
EINECS	Contact for details

Quality Control

Our production of 4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile, 2-Amino-4-(2-Chlorophenyl)-7-Methyl-5-Oxo- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP (current Good Manufacturing Practice) standards for advanced intermediates and can provide material suitable for use in regulated pre-clinical and clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.