Description

Guanidine,n-Cyano-N'-(4-Cyanophenyl)-N''-[(1R)-1,2,2-Trimethylpropyl]- is a specialized guanidine derivative featuring multiple cyano groups and a chiral, branched alkyl substituent, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in fields requiring high-purity, structurally complex building blocks with specific stereochemistry. It is primarily sought by pharmaceutical, agrochemical, and advanced materials scientists for applications in catalyst development, ligand synthesis, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Catalyst & Ligand Synthesis: The guanidine core and cyano groups make it a precursor for creating novel organocatalysts and metal-chelating ligands.
• Advanced Material Development: Employed in research for high-performance polymers, resins, or liquid crystal materials requiring rigid, functionalized monomers.
• Chemical Biology Probes: Useful for designing molecular probes and inhibitors that target specific enzymes or biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	Guanidine,n-Cyano-N'-(4-Cyanophenyl)-N''-[(1R)-1,2,2-Trimethylpropyl]-
CAS No.	220641-11-2
Molecular Formula	C16H19N5
Molecular Weight	281.36 g/mol
Synonyms	N-Cyano-N'-(4-cyanophenyl)-N''-[(1R)-1,2,2-trimethylpropyl]guanidine; (R)-N-Cyano-N'-(4-cyanophenyl)-N''-(1,2,2-trimethylpropyl)guanidine; 1-Cyano-3-(4-cyanophenyl)-1-[(1R)-1,2,2-trimethylpropyl]guanidine; Guanidine, N-cyano-N'-(4-cyanophenyl)-N''-[(1R)-1,2,2-trimethylpropyl]-; (1R)-1,2,2-Trimethylpropyl N-cyano-N'-(4-cyanophenyl)carbamimidate
EINECS	Contact for details

Quality Control

Our production of Guanidine,n-Cyano-N'-(4-Cyanophenyl)-N''-[(1R)-1,2,2-Trimethylpropyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.