Description

Pentanedioic Acid, 1-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl] Ester is a high-purity chiral ester derivative of glutaric acid and menthol. This compound is valued for its role as a key synthetic intermediate and chiral building block in advanced organic synthesis. It is primarily sought after by research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing complex stereochemistry.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereoisomers often exhibit superior biological activity.
• Fine Chemical Manufacturing: Acts as a building block for creating specialty chemicals, including chiral ligands for catalysis, flavors, and fragrances with specific olfactory profiles.
• Academic & Industrial Research: Employed in chemical research for method development, asymmetric synthesis studies, and the exploration of new reaction pathways involving ester derivatives.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or liquid crystals where the menthol moiety imparts specific physical properties.

Basic Information

Product Name	Pentanedioic Acid, 1-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl] Ester
CAS No.	220621-22-7
Molecular Formula	C15H26O4
Molecular Weight	270.37 g/mol
Synonyms	(1R,2S,5R)-Menthyl Glutarate; L-Menthyl Glutarate; (-)-Menthyl Glutarate; Glutaric Acid Menthyl Ester; Pentanedioic Acid, 1-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl] Ester; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-oxopentanoate; Menthol Glutarate Ester
EINECS	Contact for details

Quality Control

Our production of this chiral ester adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity, and impurity profile is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.