Description

3-Oxatricyclo[3.2.1.02,4]Octane-6-Methanamine (9Ci) is a specialized bicyclic amine compound featuring a unique bridged ether-oxygen structure, making it a valuable and versatile chiral building block in advanced organic synthesis. Its rigid, three-dimensional scaffold is prized for introducing conformational constraint and specific stereochemistry into target molecules, which is critical for modulating biological activity and physical properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where its constrained structure can enhance target specificity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity in critical bond-forming reactions.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require specific, rigid molecular architectures.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry and for constructing complex molecular frameworks in natural product total synthesis.

Basic Information

Product Name	3-Oxatricyclo[3.2.1.02,4]Octane-6-Methanamine (9Ci)
CAS No.	220555-34-0
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Synonyms	6-(Aminomethyl)-3-oxatricyclo[3.2.1.02,4]octane; 3-Oxatricyclo[3.2.1.02,4]octane-6-methanamine; 6-Aminomethyl-3-oxatricyclo[3.2.1.02,4]octane; Bicyclic amine ether; 2,4-Didehydro-3-oxa-adamantan-6-ylmethanamine; (1R,5S,6r)-6-(Aminomethyl)-3-oxatricyclo[3.2.1.02,4]octane (stereoisomer); 220555-34-0; 3-Oxa-tricyclo[3.2.1.02,4]octane-6-methanamine
EINECS	Contact for details

Quality Control

Our 3-Oxatricyclo[3.2.1.02,4]Octane-6-Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, to ensure it meets the high standards required for research and process development. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.