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2-(7-Chloro-5-Methyl-4-Oxo-3-Phenyl-4,5-Dihydro-3H-Pyridazino[4,5-B]Indol-1-Yl)-N,n-Dimethylacetamide CAS NO 220448-02-2


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CAS No.:220448-02-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(7-Chloro-5-Methyl-4-Oxo-3-Phenyl-4,5-Dihydro-3H-Pyridazino[4,5-B]Indol-1-Yl)-N,n-Dimethylacetamide is a high-purity, complex heterocyclic organic compound with significant potential as a key synthetic intermediate in advanced pharmaceutical research. Its intricate molecular architecture makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology. This compound is essential for research chemists and process development scientists in pharmaceutical and biotechnology companies engaged in cutting-edge drug discovery and synthesis programs.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those with indole and pyridazine core structures.
  • Drug Discovery Research: Used as a scaffold or building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
  • Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators for pharmacological research.
  • Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for potential new chemical entities (NCEs).
  • Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.
  • Academic Research: Used in university and institutional labs for synthetic organic chemistry studies and the exploration of new heterocyclic reaction methodologies.

Basic Information

Item Detail
Product Name 2-(7-Chloro-5-Methyl-4-Oxo-3-Phenyl-4,5-Dihydro-3H-Pyridazino[4,5-B]Indol-1-Yl)-N,n-Dimethylacetamide
CAS No. 220448-02-2
Molecular Formula C21H19ClN4O2
Molecular Weight 394.86 g/mol
Synonyms N,N-Dimethyl-2-[(7-chloro-5-methyl-4-oxo-3-phenyl-4,5-dihydro-3H-pyridazino[4,5-b]indol-1-yl)]acetamide; 1-[2-(Dimethylamino)-2-oxoethyl]-7-chloro-5-methyl-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indol-4-one; 220448-02-2; Pyridazino[4,5-b]indole acetamide derivative; CAS 220448-02-2
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Quality Control

Our 2-(7-Chloro-5-Methyl-4-Oxo-3-Phenyl-4,5-Dihydro-3H-Pyridazino[4,5-B]Indol-1-Yl)-N,n-Dimethylacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect the compound's integrity.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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