Description

(R,E)-2-Methyl-n-(3-Methylbutylidene)Propane-2-Sulfinamide is a high-purity chiral sulfinamide building block, a critical intermediate in asymmetric synthesis. Its primary value lies in its role as a versatile and stereoselective ammonia equivalent for the preparation of enantiomerically pure amines, which are foundational to modern pharmaceutical development. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries engaged in the synthesis of active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral auxiliary and building block in the asymmetric synthesis of complex amine-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry is crucial for activity.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of chiral catalysts and ligands used in enantioselective transformations.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry, particularly in studies involving sulfinimines and nucleophilic addition reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	(R,E)-2-Methyl-n-(3-Methylbutylidene)Propane-2-Sulfinamide
CAS No.	220315-20-8
Molecular Formula	C9H19NOS
Molecular Weight	189.32 g/mol
Synonyms	(R,E)-2-Methyl-N-(3-methylbutylidene)propane-2-sulfinamide; (R,E)-N-(3,3-Dimethylbutylidene)-2-methylpropane-2-sulfinamide; (R,E)-tert-Butanesulfinamide, N-(3,3-dimethylbutylidene)-; (R,E)-N-(3-Methylbutylidene)-2-methylpropane-2-sulfinamide; (R,E)-N-(3,3-Dimethylbutylidene)-2-methyl-2-propanesulfinamide; (R,E)-2-Methyl-2-propanesulfinamide, N-(3,3-dimethylbutylidene)-; (R,E)-tert-Butylsulfinyl Imine Derivative; (R,E)-Sulfinimine Chiral Auxiliary
EINECS	Contact for details

Quality Control

Our (R,E)-2-Methyl-n-(3-Methylbutylidene)Propane-2-Sulfinamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/LC-MS, to ensure high chemical and enantiomeric purity consistent with R&D and process chemistry requirements. Certificates of Analysis (COA) with full analytical data are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.