Description

5-Bromo-2-(trifluoromethyl)-1H-imidazole is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents on the imidazole core, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a building block for creating specialized polymers, ligands, and organic electronic materials with tailored properties.
• Chemical Biology & Medicinal Chemistry: Employed in fragment-based drug discovery and the synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-2-(trifluoromethyl)-1H-imidazole
CAS No.	219534-98-2
Molecular Formula	C4H2BrF3N2
Molecular Weight	214.97 g/mol
Synonyms	5-Bromo-2-(trifluoromethyl)imidazole; 2-(Trifluoromethyl)-5-bromo-1H-imidazole; 1H-Imidazole, 5-bromo-2-(trifluoromethyl)-; 5-Bromo-2-trifluoromethylimidazole; 5-Bromo-2-(trifluoromethyl)-1H-imidazole; 219534-98-2; 5-Br-2-CF3-Imidazole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 5-Bromo-2-(trifluoromethyl)-1H-imidazole adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability for your critical R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.