Description

n-(4,6-Dimethylpyrimidin-2-Yl)-4-(1,3-Dioxo-1,3,3A,4,7,7A-Hexahydro-2H-4,7-Methanoisoindol-2-Yl)Benzenesulfonamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug molecules, especially for central nervous system (CNS) or anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides or pesticides, leveraging its sulfonamide and pyrimidine motifs for biological activity.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• API Development: Employed in the pilot-scale and commercial-scale synthesis of target active pharmaceutical ingredients requiring this specific benzenesulfonamide derivative.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study specific enzyme pathways.

Basic Information

Product Name	n-(4,6-Dimethylpyrimidin-2-Yl)-4-(1,3-Dioxo-1,3,3A,4,7,7A-Hexahydro-2H-4,7-Methanoisoindol-2-Yl)Benzenesulfonamide
CAS No.	217490-20-5
Molecular Formula	C21H21N5O4S
Molecular Weight	439.49 g/mol
Synonyms	4-(1,3-Dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide; 2-[[4-[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione; N-(4,6-dimethylpyrimidin-2-yl)-4-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)benzenesulfonamide; Benzenesulfonamide, N-(4,6-dimethyl-2-pyrimidinyl)-4-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methano-2-isoindolyl)-; 217490-20-5
EINECS	Contact for details

Quality Control

Our n-(4,6-Dimethylpyrimidin-2-Yl)-4-(1,3-Dioxo-1,3,3A,4,7,7A-Hexahydro-2H-4,7-Methanoisoindol-2-Yl)Benzenesulfonamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.