Description

4-(N',N'-Diboc-Aminomethyl)-n-Hydroxybenzamidine is a specialized, high-purity chemical building block primarily used in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceutical candidates and bioactive molecules, particularly those targeting protease enzymes. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex multi-step syntheses. The product is supplied with full analytical documentation to ensure batch-to-batch consistency and support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially protease inhibitors.
• Bioconjugation & Probe Development: Used in the creation of chemical probes and affinity labels for biochemical and proteomic research.
• Peptidomimetic Synthesis: Serves as a core scaffold for constructing peptidomimetic compounds that mimic natural peptides.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize lead compounds.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic and bioorganic chemistry.

Basic Information

Product Name	4-(N',N'-Diboc-Aminomethyl)-n-Hydroxybenzamidine
CAS No.	217313-83-2
Molecular Formula	C20H31N3O6
Molecular Weight	409.48 g/mol
Synonyms	4-[(Di-tert-butoxycarbonylamino)methyl]-N-hydroxybenzenecarboximidamide; 4-(N,N-Bis-Boc-aminomethyl)benzamidoxime; 4-[(Bis(tert-butoxycarbonyl)amino)methyl]benzamidoxime; 4-(N,N-Di-Boc-aminomethyl)benzamidoxime; 4-(Bis-Boc-aminomethyl)benzamidoxime; 4-[(Di-Boc-amino)methyl]benzamidoxime; 4-(N',N'-Diboc-aminomethyl)benzamidoxime; 4-(N,N-Di-tert-butoxycarbonylaminomethyl)benzamidoxime
EINECS	Contact for details

Quality Control

Every batch of 4-(N',N'-Diboc-Aminomethyl)-n-Hydroxybenzamidine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and conformity with customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.