Description

4-Amino-Tetrahydro-Pyran-4-Carboxylic Acid Hcl CAS NO 217299-03-1 is a high-purity, pharmaceutically relevant building block characterized by its unique cyclic ether and amino acid functionality. This compound is a critical intermediate in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical manufacturers developing new therapeutic agents, particularly in areas requiring chiral, constrained amino acid analogs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially protease inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities for drug candidates.
• Peptidomimetics Development: Serves as a constrained, non-proteinogenic amino acid analog in the design of peptide mimics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of specialized molecules used to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	4-Amino-Tetrahydro-Pyran-4-Carboxylic Acid Hydrochloride
CAS No.	217299-03-1
Molecular Formula	C7H14ClNO3
Molecular Weight	195.64 g/mol
Synonyms	4-Aminooxane-4-carboxylic acid hydrochloride; 4-Aminotetrahydropyran-4-carboxylic acid HCl; 4-Amino-THP-4-COOH·HCl; 4-Amino-4-carboxytetrahydropyran hydrochloride; 4-Aminotetrahydro-2H-pyran-4-carboxylic acid hydrochloride; (4-Aminotetrahydro-2H-pyran-4-yl)formic acid hydrochloride; 4-Amino-4-pyrancarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-Tetrahydro-Pyran-4-Carboxylic Acid Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.