Description

Cyclopentanecarboxylic Acid, 2-Hydroxy-, Hydrazide, (1R,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid hydrazide and a hydroxyl group on a cyclopentane ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. Its defined stereochemistry at the 1R,2S positions is critical for applications requiring precise three-dimensional control over the final product's biological activity and properties.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for constructing constrained ring systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where its specific stereochemistry can influence biological efficacy.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: The hydrazide moiety is valuable for creating peptide analogs and conformationally restricted peptidomimetics in medicinal chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial research applications.
• Academic and R&D Laboratories: Used as a reference standard and building block in chemical research exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Hydroxy-, Hydrazide, (1R,2S)- (9Ci)
CAS No.	216879-03-7
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	(1R,2S)-2-Hydroxycyclopentanecarbohydrazide; (1R,2S)-2-Hydroxycyclopentane-1-carbohydrazide; (1R,2S)-2-Hydroxy-1-cyclopentanecarboxylic acid hydrazide; (1R,2S)-rel-2-Hydroxycyclopentanecarboxylic acid hydrazide; Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, (1R,2S)-; (1R,2S)-2-Hydroxycyclopentylcarbohydrazide
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Hydroxy-, Hydrazide, (1R,2S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identification. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced R&D customers. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this moisture-sensitive compound from humidity. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2S)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.