Description

6-Hydroxy-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is a versatile indane derivative carboxylic acid that serves as a critical building block in advanced organic synthesis. Its unique fused bicyclic structure with both phenolic and carboxylic acid functionalities makes it a valuable intermediate for creating complex molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators, leveraging its rigid indane core.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis or metal-organic frameworks (MOFs) due to its bifunctional (acid and phenol) nature.
• Material Science Research: Building block for specialty polymers, dyes, or organic electronic materials where thermal stability and specific optical properties are required.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	6-Hydroxy-2,3-Dihydro-1H-Indene-1-Carboxylic Acid
CAS No.	216582-47-7
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	1H-Indene-1-carboxylic acid, 2,3-dihydro-6-hydroxy-; 6-Hydroxyindane-1-carboxylic acid; 6-Hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid; 1-Carboxy-6-hydroxyindane; 6-Hydroxyhydrindene-1-carboxylic acid; 6-HO-Indane-1-COOH; 216582-47-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.