Description

2H-Pyran-6-Carboxylicacid,2-Ethoxy-3,4-Dihydro-4-Methyl-,Ethylester,(2R,4R)-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the construction of advanced, stereoselective pesticide and herbicide molecules.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and molecular scaffolds.
• Material Science: Potential precursor for the synthesis of specialized polymers or functional organic materials.

Basic Information

Product Name	2H-Pyran-6-Carboxylicacid,2-Ethoxy-3,4-Dihydro-4-Methyl-,Ethylester,(2R,4R)-(9Ci)
CAS No.	216220-75-6
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	(2R,4R)-2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic acid ethyl ester; Ethyl (2R,4R)-2-ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylate; 2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic Acid Ethyl Ester, (2R,4R)-; (2R,4R)-Rel-2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic Acid Ethyl Ester; 216220-75-6; (2R,4R)-DHP Ester
EINECS	Contact for details

Quality Control

Our 2H-Pyran-6-Carboxylicacid,2-Ethoxy-3,4-Dihydro-4-Methyl-,Ethylester,(2R,4R)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2R,4R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.