Description

(S)-2-Amino-3-(4-Isopropyl-Phenyl)Propionic Acid CAS NO 216007-00-0 is a high-purity, non-natural amino acid derivative featuring a chiral center and an isopropyl-substituted aromatic side chain. This compound is a critical chiral building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorders.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate a hydrophobic, sterically defined amino acid residue into peptide sequences.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for probing protein-ligand interactions due to its specific stereochemistry.
• Agrochemical Development: Potential use as a precursor in the synthesis of chiral herbicides or plant growth regulators.
• Material Science: Investigation into its incorporation into specialty polymers or organic frameworks for advanced material properties.

Basic Information

Item	Detail
Product Name	(S)-2-Amino-3-(4-Isopropyl-Phenyl)Propionic Acid
CAS No.	216007-00-0
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	(S)-2-Amino-3-(4-isopropylphenyl)propanoic acid; (S)-4-Isopropylphenylalanine; D-4-Isopropylphenylalanine; (S)-p-Isopropylphenylalanine; H-Phe(4-iPr)-OH; (S)-α-Amino-4-isopropylbenzenepropanoic acid; (2S)-2-Amino-3-[4-(propan-2-yl)phenyl]propanoic acid; Fmoc-Phe(4-iPr)-OH (protected form)
EINECS	Contact for details

Quality Control

Every batch of (S)-2-Amino-3-(4-Isopropyl-Phenyl)Propionic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity (typically ≥98% by HPLC), chiral purity (≥99% ee), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.