Description

trans-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry to construct complex heterocyclic scaffolds and bioactive molecules.
• Chemical Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and other high-value, complex organic compounds.

Basic Information

Product Name	trans-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride
CAS No.	215941-06-3
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	trans-4-Amino-3-hydroxytetrahydro-2H-pyran hydrochloride; (3R,4R)-4-Amino-3-hydroxytetrahydro-2H-pyran hydrochloride; (3S,4S)-4-Amino-3-hydroxytetrahydro-2H-pyran hydrochloride; 4-Amino-3-hydroxytetrahydropyran hydrochloride; 3-Hydroxy-4-aminotetrahydropyran HCl; THP-Amino Alcohol Hydrochloride; 215941-06-3; 4-Aminotetrahydro-2H-pyran-3-ol hydrochloride, trans-
EINECS	Contact for details

Quality Control

Our trans-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.