Description

[(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene is a chiral ferrocene-based oxazoline ligand, a sophisticated organometallic compound prized for its role in asymmetric synthesis. This product is essential for enabling highly selective catalytic transformations, particularly in the pharmaceutical and fine chemical industries where stereochemical purity is paramount. It is a critical reagent for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials requiring precise enantiomeric control.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation, hydrosilylation, and cross-coupling reactions.
• Key intermediate in the research and development of pharmaceutical compounds requiring high enantiomeric excess (ee).
• Utilized in the synthesis of advanced materials and specialty chemicals with specific stereochemical properties.
• Critical component for academic and industrial R&D in organometallic chemistry and catalysis.
• Potential use in the development of agrochemicals and flavors/fragrances where chiral selectivity is required.
• As a reference standard for analytical method development and quality control in chiral synthesis.

Basic Information

Product Name	[(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene
CAS No.	215818-63-6
Molecular Formula	C19H17FeNO
Molecular Weight	331.19 g/mol
Synonyms	(R)-4-Phenyl-4,5-dihydro-2-ferrocenyloxazole; (R)-4-Phenyl-2-ferrocenyl-4,5-dihydrooxazole; (R)-2-(Ferrocenyl)-4-phenyl-4,5-dihydrooxazole; (R)-PFBO; (R)-Ferrocenyloxazoline; (4R)-4-Phenyl-4,5-dihydro-2-(ferrocen-1-yl)-1,3-oxazole; (R)-4,5-Dihydro-4-phenyl-2-(ferrocenyl)oxazole; Chiral Ferrocenyl Oxazoline Ligand
EINECS	Contact for details

Quality Control

Our [(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of research and process chemistry. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.