Description

1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Benzoyl-D-Ribofuranose is a key protected ribofuranose derivative, serving as a critical chiral building block in synthetic organic chemistry. Its value lies in its functionalized structure, which provides multiple reactive handles for the controlled synthesis of complex nucleoside analogs and carbohydrate-based molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of antiviral agents, modified oligonucleotides, and other bioactive compounds.

Application

• Nucleoside Analog Synthesis: A vital intermediate for constructing modified nucleosides with potential antiviral or anticancer activity.
• Oligonucleotide Chemistry: Used in the preparation of sugar-modified oligonucleotides for antisense therapy and diagnostic applications.
• Carbohydrate Chemistry Research: Serves as a versatile starting material for the synthesis of complex, azido-functionalized sugars and glycoconjugates.
• Pharmaceutical Intermediate: Employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting viral diseases.
• Click Chemistry Substrate: The azido group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer chemistry.
• Glycobiology Studies: Useful for probing biological processes involving carbohydrate recognition and metabolism.

Basic Information

Product Name	1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Benzoyl-D-Ribofuranose
CAS No.	215176-56-0
Molecular Formula	C16H17N3O7
Molecular Weight	363.33 g/mol
Synonyms	1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-benzoyl-D-ribofuranose; 3-Azido-1,2-di-O-acetyl-3-deoxy-5-O-benzoyl-D-ribofuranose; 3-Azido-3-deoxy-1,2-di-O-acetyl-5-O-benzoyl-D-ribofuranose; 3-Azido-5-O-benzoyl-1,2-di-O-acetyl-3-deoxy-D-ribofuranose; 1,2-Di-O-acetyl-3-azido-5-O-benzoyl-3-deoxy-D-ribofuranose; D-Ribofuranose, 3-azido-1,2-di-O-acetyl-3-deoxy-5-O-benzoate
EINECS	Contact for details

Quality Control

Our 1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Benzoyl-D-Ribofuranose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.