Description

1,1-Dimethyl-2,3-Bis(tert-Butyloxycarbonyl)Guanidine is a high-purity, protected guanidine derivative widely used as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel drug candidates, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing guanidine or amidine functional groups.
• Peptidomimetic Synthesis: Used to introduce protected guanidine moieties into peptide analogs and peptidomimetics, which are important for drug discovery targeting various diseases.
• Agrochemical Development: Serves as an intermediate in the research and production of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Polymer Chemistry: Can be utilized as a monomer or functionalization agent for creating specialty polymers with specific chemical properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing dimethylguanidine groups under mild, protected conditions in multi-step syntheses.

Basic Information

Product Name	1,1-Dimethyl-2,3-Bis(tert-Butyloxycarbonyl)Guanidine
CAS No.	215170-99-3
Molecular Formula	C₁₄H₂₇N₃O₄
Molecular Weight	301.38 g/mol
Synonyms	N,N-Dimethyl-N',N''-bis(tert-butoxycarbonyl)guanidine; Di-Boc-dimethylguanidine; 1,1-Dimethyl-2,3-bis[(2-methyl-2-propanyl)oxycarbonyl]guanidine; 2,3-Bis(tert-butoxycarbonyl)-1,1-dimethylguanidine; (tert-Butoxycarbonyl)₂-dimethylguanidine; Boc₂-Dimethylguanidine; Guanidine, 1,1-dimethyl-2,3-bis[(2-methyl-2-propanyl)oxycarbonyl]-
EINECS	Contact for details

Quality Control

Our 1,1-Dimethyl-2,3-Bis(tert-Butyloxycarbonyl)Guanidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.