Description

Ethyl 6-Chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylate is a high-value, multi-functional chemical intermediate characterized by its chromene core and trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of advanced molecules, offering a unique combination of structural features for fine-tuning biological activity and material properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Acts as a monomer or additive in the research of specialty polymers, coatings, and liquid crystals to impart specific optical or electronic properties.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Fluorine Chemistry Studies: Utilized as a model compound in research focused on the introduction and reactivity of fluorine-containing motifs in organic molecules.

Basic Information

Item	Detail
Product Name	Ethyl 6-Chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylate
CAS No.	215123-85-6
Molecular Formula	C₁₃H₁₀ClF₃O₃
Molecular Weight	306.66 g/mol
Synonyms	6-Chloro-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid ethyl ester; Ethyl 6-chloro-2-(trifluoromethyl)chromene-3-carboxylate; 2H-1-Benzopyran-3-carboxylic acid, 6-chloro-2-(trifluoromethyl)-, ethyl ester; 6-Chloro-2-trifluoromethyl-2H-chromene-3-carboxylic acid ethyl ester; 215123-85-6; Chromene-3-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.