Description

2H-Pyran-2-One,Tetrahydro-3-Methyl-6-(1-Methylethyl)-,(3R,6S)-(9Ci) is a high-purity, stereochemically defined lactone compound, identified by CAS NO 213899-37-7, that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry at the 3R and 6S positions makes it invaluable for creating molecules with specific three-dimensional architectures, which is essential for achieving desired biological activity or material properties. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical purity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the specific stereoisomer can influence efficacy and environmental profile.
• Fine Chemical Building Block: Employed in the synthesis of complex fragrances, flavors, and specialty chemicals that benefit from its lactone structure and defined chirality.
• Academic & Industrial Research: Serves as a standard or starting material in methodological development for asymmetric synthesis and catalysis studies.
• Material Science Precursor: Potential use in the synthesis of monomers for specialized polymers or advanced organic materials.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-3-Methyl-6-(1-Methylethyl)-,(3R,6S)-(9Ci)
CAS No.	213899-37-7
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(3R,6S)-3-Methyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; (3R,6S)-3-Methyl-6-isopropyltetrahydro-2H-pyran-2-one; (3R,6S)-Dihydro-3-methyl-6-(1-methylethyl)-2H-pyran-2-one; Tetrahydro-3-methyl-6-(1-methylethyl)-2H-pyran-2-one, (3R,6S)-; (3R,6S)-rel-3-Methyl-6-(1-methylethyl)tetrahydro-2H-pyran-2-one; Stereoisomer of 3-Methyl-6-isopropyltetrahydro-2H-pyran-2-one; Chiral Lactone Intermediate 213899-37-7
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high stereochemical purity, which is critical for downstream synthesis. Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.