Description

5-(4-Chlorophenyl)-2,2-Dimethyl-3-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Pentanediol is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure containing both a chlorophenyl and a triazole moiety. This compound is of significant commercial importance for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antifungal and other therapeutic agents. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in process development and scale-up for new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multistep synthesis of complex antifungal APIs and other bioactive molecules.
• Agrochemical Research: Used in the development and synthesis of novel fungicides and plant protection agents, leveraging its triazole functional group.
• Chemical Synthesis: Acts as a versatile chiral building block for organic chemists in academia and industry for constructing complex molecular architectures.
• Process Development & Scale-Up: Supplied to R&D and pilot plant facilities for optimizing synthetic routes and ensuring robust, reproducible manufacturing processes.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling of related pharmaceutical compounds.

Basic Information

Product Name	5-(4-Chlorophenyl)-2,2-Dimethyl-3-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Pentanediol
CAS No.	212267-64-6
Molecular Formula	C16H22ClN3O2
Molecular Weight	323.82 g/mol
Synonyms	1,3-Pentanediol, 5-(4-chlorophenyl)-2,2-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)-; 5-(p-Chlorophenyl)-2,2-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentane-1,3-diol; (3R,5R)-5-(4-Chlorophenyl)-2,2-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)-1,3-pentanediol (for specific stereoisomers); Triazole Diol Intermediate; Antifungal Intermediate CP-TZD
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-2,2-Dimethyl-3-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Pentanediol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) documenting purity, chiral purity (where applicable), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.