Description

3,6-Dioxaoctane-1,8-Diyl Bismethanethiosulfonate is a specialized bifunctional thiosulfonate compound, primarily valued as a versatile cross-linking and functionalization agent in advanced material synthesis. Its core value lies in its ability to introduce disulfide or thiol-reactive groups, enabling the precise modification of polymers, surfaces, and biomolecules. This product is essential for researchers and manufacturers in the pharmaceutical, polymer science, and bioconjugation sectors who require controlled chemical linkage and stability.

Application

• Polymer Modification & Cross-linking: Used to introduce reactive thiosulfonate groups into polymer backbones for creating hydrogels, elastomers, and self-healing materials.
• Bioconjugation & Protein Engineering: Serves as a linker for attaching peptides, drugs, or labels to antibodies, proteins, and other biomolecules under mild conditions.
• Surface Functionalization: Applied to modify the surface of nanoparticles, gold surfaces, or medical devices to enhance biocompatibility or enable further chemical grafting.
• Pharmaceutical Intermediate: Acts as a key synthetic building block in the development of prodrugs and drug delivery systems that utilize disulfide bonds for targeted release.
• Material Science Research: Employed in R&D for developing novel responsive materials and studying disulfide exchange kinetics and dynamics.

Basic Information

Product Name	3,6-Dioxaoctane-1,8-Diyl Bismethanethiosulfonate
CAS No.	212262-04-9
Molecular Formula	C8H14O6S4
Molecular Weight	334.44 g/mol
Synonyms	Bis(methanethiosulfonate) PEG2; 1,8-Bis(methanesulfonothioyl)-3,6-dioxaoctane; PEG2 dithiosulfonate; DTSSP crosslinker analog; 3,6-Dioxaoctane-1,8-diyl bis(methanesulfonothioate); Ethylene glycol bis(2-methanethiosulfonateethyl) ether; Bis-MTS-PEG2
EINECS	Contact for details

Quality Control

Our 3,6-Dioxaoctane-1,8-Diyl Bismethanethiosulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets high-purity research and production standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.