Description

Ethanone, 1-[(1R,3R)-3-Hydroxy-1-Methylcyclopentyl]-, Rel- (9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, optically active molecules, particularly within the pharmaceutical sector. It is needed by research and development chemists and process scale-up teams in the fine chemical and pharmaceutical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials where specific stereochemistry is required.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the commercial-scale production of high-value chiral compounds.
• Academic & Industrial Research: Used in methodological studies and the development of new synthetic transformations in organic chemistry laboratories.

Basic Information

Product Name	Ethanone, 1-[(1R,3R)-3-Hydroxy-1-Methylcyclopentyl]-, Rel- (9Ci)
CAS No.	211875-85-3
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	rel-(1R,3R)-3-Hydroxy-1-methylcyclopentyl methyl ketone; (1R,3R)-3-Hydroxy-1-methylcyclopentyl methyl ketone (rel); 1-[(1R,3R)-3-Hydroxy-1-methylcyclopentyl]ethanone; (rel)-(1R,3R)-3-Hydroxy-1-methylcyclopentyl methyl ketone; 3-Hydroxy-1-methylcyclopentyl methyl ketone (rel); CAS 211875-85-3; Chiral hydroxy ketone intermediate
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[(1R,3R)-3-Hydroxy-1-Methylcyclopentyl]-, Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (by HPLC/GC), enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e. (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.