Description

4H-Pyrano[3,4-D]Oxazol-2(3H)-One,Tetrahydro-6-Hydroxy-7-Methoxy-4,7A- is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing diverse chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in academic and industrial R&D for the construction of novel pyran-oxazole fused ring systems, which are of significant interest in heterocyclic chemistry.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential new chemical entities (NCEs).
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or conjugates for biochemical and diagnostic applications due to its functionalizable hydroxy and carbonyl groups.

Basic Information

Product Name	4H-Pyrano[3,4-D]Oxazol-2(3H)-One,Tetrahydro-6-Hydroxy-7-Methoxy-4,7A-
CAS No.	211804-27-2
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	6-Hydroxy-7-methoxy-4,7a-tetrahydro-4H-pyrano[3,4-d]oxazol-2(3H)-one; Tetrahydro-6-hydroxy-7-methoxy-4H-pyrano[3,4-d]oxazol-2(3H)-one; 4H-Pyrano[3,4-d]oxazol-2(3H)-one, tetrahydro-6-hydroxy-7-methoxy-; 211804-27-2; 6-Hydroxy-7-methoxy-4,7a-tetrahydro-4H-pyrano[3,4-d][1,3]oxazol-2-one; Fused pyran-oxazolone derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.