Description

n-Methoxy-4-Nitrobenzenesulfonamide is a specialized aromatic sulfonamide derivative, serving as a crucial synthetic intermediate and protecting group reagent in advanced organic synthesis. Its value lies in its unique chemical structure, which allows for selective reactions and the construction of complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly those containing sulfonamide pharmacophores.
• Building block for agrochemical research, aiding in the development of novel herbicides and fungicides.
• Useful reagent in material science for creating specialty polymers and advanced organic frameworks.
• Employed as a protecting group for amines in multi-step synthetic routes due to its ortho-nitro methoxy benzene sulfonyl (o-NMBS) character.
• Valuable substrate in methodological chemistry research for studying new sulfonylation or amidation reactions.
• Starting material for the preparation of more complex sulfonamide-based chemical libraries for high-throughput screening.

Basic Information

Product Name	n-Methoxy-4-Nitrobenzenesulfonamide
CAS No.	211675-81-9
Molecular Formula	C7H8N2O5S
Molecular Weight	232.21 g/mol
Synonyms	4-Nitro-m-anisolesulfonamide; 2-Methoxy-5-nitrobenzenesulfonamide; o-Nitroanisole-4-sulfonamide; 4-Nitro-2-methoxybenzenesulfonamide; NMBS; o-NMBS; 2-Methoxy-5-nitrobenzene-1-sulfonamide; Benzenesulfonamide, 2-methoxy-5-nitro-
EINECS	Contact for details

Quality Control

Our n-Methoxy-4-Nitrobenzenesulfonamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.