Description

Z-D-Arg(Mtr)-Oh Cha is a protected arginine derivative, specifically the Z-protected form of D-arginine with the Mtr (4-methoxy-2,3,6-trimethylbenzenesulfonyl) side-chain protecting group. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, where it provides precise stereochemical control and side-chain functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, drug discovery, and the development of therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-arginine residues into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including enzyme inhibitors and receptor agonists/antagonists.
• Bioconjugation: Serves as a modified amino acid for creating labeled peptides or peptide-biomolecule conjugates for diagnostic and research purposes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify novel bioactive compounds.
• Academic Research: A valuable reagent for studying peptide structure-activity relationships and for methodological development in organic synthesis.

Basic Information

Product Name	Z-D-Arg(Mtr)-Oh Cha
CAS No.	210557-94-1
Molecular Formula	C30H41N5O8S
Molecular Weight	631.74 g/mol
Synonyms	Z-D-Arg(Mtr)-OH; Nα-Z-Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine; Benzyloxycarbonyl-Nω-(4-methoxy-2,3,6-trimethylphenylsulfonyl)-D-arginine; D-Arg(Mtr)-Z-OH; Z-D-Arg(Mtr); Fmoc-D-Arg(Mtr)-OH precursor; Nα-Carbobenzyloxy-Nω-(Mtr)-D-arginine; Protected D-Arginine derivative
EINECS	Contact for details

Quality Control

Our Z-D-Arg(Mtr)-Oh Cha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.