Description

4-Aminotetrahydro-2H-Thiopyran 1,1-Dioxide is a high-purity, functionalized sulfone derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a sulfone group and a primary amine, makes it an invaluable intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific sulfone-based bioactive cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with tailored electronic or structural properties.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functional group manipulation.

Basic Information

Product Name	4-Aminotetrahydro-2H-Thiopyran 1,1-Dioxide
CAS No.	210240-20-3
Molecular Formula	C5H11NO2S
Molecular Weight	149.21 g/mol
Synonyms	4-Aminothiane 1,1-dioxide; 4-Aminotetrahydrothiopyran 1,1-dioxide; 4-Aminothiacyclohexane 1,1-dioxide; 1,1-Dioxo-1λ⁶-thiane-4-amine; 4-Amino-1-thioniabicyclo[2.2.2]octane 1,1-dioxide; Tetrahydro-4-amino-2H-thiopyran 1,1-dioxide; 4-Amino-thiane-1,1-dioxide
EINECS	Contact for details

Quality Control

Every batch of 4-Aminotetrahydro-2H-Thiopyran 1,1-Dioxide is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, chiral purity (where applicable), and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is available for each lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.