Description

(2S,3R)-3-Methyl-2-(p-Tolyl)Chroman-4-One is a high-purity chiral chromanone derivative, a key structural motif in organic synthesis. This compound is valued for its role as a sophisticated pharmaceutical intermediate and a versatile building block in the development of complex molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Asymmetric Synthesis Building Block: Utilized in stereoselective reactions to construct complex molecular architectures with defined three-dimensional configurations.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Agrochemical Development: Used in the research and synthesis of novel, optically active crop protection agents.
• Catalyst and Ligand Synthesis: Acts as a starting material for the preparation of chiral ligands or organocatalysts used in enantioselective transformations.
• Academic and Industrial R&D: Employed in chemical research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	(2S,3R)-3-Methyl-2-(p-Tolyl)Chroman-4-One
CAS No.	210049-98-2
Molecular Formula	C17H16O2
Molecular Weight	252.31 g/mol
Synonyms	(2S,3R)-3-Methyl-2-(4-methylphenyl)-4-chromanone; (2S,3R)-3-Methyl-2-(p-tolyl)chroman-4-one; 4H-1-Benzopyran-4-one, 2-(4-methylphenyl)-3-methyl-, (2S,3R)-; (2S,3R)-2-(4-Methylphenyl)-3-methyl-4-chromanone; (2S,3R)-3-Methyl-2-(4-methylphenyl)-4H-chromen-4-one; (2S,3R)-3-Methyl-2-(p-tolyl)-4-chromanone; (2S,3R)-3-Methyl-2-(4-tolyl)chroman-4-one; (2S,3R)-3-Methyl-2-(p-methylphenyl)-4-chromanone
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-Methyl-2-(p-Tolyl)Chroman-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be handled under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.