Description

[(1S)-Endo]-(+)-3-Bromo-10-Camphorsulfonic Acid Monohydrate is a high-purity, chiral sulfonic acid derivative of camphor, widely recognized as a versatile chiral resolving agent and catalyst. Its primary value lies in its ability to facilitate the separation of enantiomers and act as a chiral auxiliary in asymmetric synthesis, which is critical for producing optically pure pharmaceutical intermediates and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemical control is paramount.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures of amines, amino acids, and other basic compounds via diastereomeric salt formation.
• Asymmetric Synthesis Catalyst: Employed as a chiral Brønsted acid catalyst in enantioselective organic transformations.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Analytical Chemistry Standard: Utilized as a reference standard in chiral HPLC and other analytical methods for method development and validation.
• Agrochemical Research: Applied in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new chiral methodologies and compounds.

Basic Information

Product Name	[(1S)-Endo]-(+)-3-Bromo-10-Camphorsulfonic Acid Monohydrate
CAS No.	209736-59-4
Molecular Formula	C₁₀H₁₅BrO₄S • H₂O
Molecular Weight	329.20 g/mol (Anhydrous basis: 311.19)
Synonyms	(+)-3-Bromocamphor-10-sulfonic Acid Monohydrate; (1S)-(+)-3-Bromo-10-camphorsulfonic Acid Hydrate; 3-Bromo-10-sulfocamphoric Acid Monohydrate; (+)-3-Bromo-10-camphorsulfonic Acid; BCSA; (1S,4R)-3-Bromo-1,7,7-trimethylbicyclo[2.2.1]heptane-2-sulfonic Acid Monohydrate
EINECS	Contact for details

Quality Control

Our [(1S)-Endo]-(+)-3-Bromo-10-Camphorsulfonic Acid Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic and analytical applications. Certificates of Analysis (COA) detailing identity, purity, and specific rotation are provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect product performance and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Specific Rotation [α]²⁰D	+40° to +44° (c=1 in H₂O)
Water Content (KF)	4.5% - 6.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.