Description

1,4-Ethano-5,8-Methanonaphthalene-10,11-Dione, 1,4,4A,5,8,8A-Hexahydro-, (1R,4S,4As,5S,8R,8Ar)-Rel- (9Ci) is a specialized, high-purity synthetic intermediate with a complex, stereochemically defined polycyclic structure. This compound matters for its role as a critical building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and functional materials. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to create complex molecular architectures with precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-cancer drug candidates.
• Agrochemical Research: Used in the development of novel, high-performance pesticides and herbicides where its unique bridged structure can impart specific biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal or optical properties.
• Asymmetric Catalysis Ligand Synthesis: Provides a rigid, chiral scaffold for the development of novel ligands used in enantioselective catalytic reactions.
• Academic & Industrial R&D: Employed in exploratory chemistry for constructing complex natural product analogs and investigating new chemical transformations.
• Fine Chemical Production: Utilized in multi-step synthesis processes for manufacturing other high-value, low-volume specialty chemicals.

Basic Information

Product Name	1,4-Ethano-5,8-Methanonaphthalene-10,11-Dione, 1,4,4A,5,8,8A-Hexahydro-, (1R,4S,4As,5S,8R,8Ar)-Rel- (9Ci)
CAS No.	208836-09-3
Molecular Formula	C₁₃H₁₄O₂
Molecular Weight	202.25 g/mol
Synonyms	(1R,4S,4aS,5S,8R,8aR)-rel-1,4,4a,5,8,8a-Hexahydro-1,4:5,8-dimethanonaphthalene-10,11-dione; rel-(1R,4S,4aS,5S,8R,8aR)-1,4:5,8-Diepoxynaphthalene-10,11-dione; 1,4:5,8-Diepoxy-1,4,4a,5,8,8a-hexahydronaphthalene-10,11-dione; Hexahydro-1,4:5,8-dimethanonaphthalene-10,11-dione; A chiral Diels-Alder adduct derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1,4-Ethano-5,8-Methanonaphthalene-10,11-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.