Description

T-Butoxycarbonyl-4-Tributylstannyl-1,2,3,6-Tetrahydropyridine is a high-purity organotin reagent featuring a protected amine group, widely utilized as a key synthetic intermediate in advanced organic synthesis. Its primary value lies in enabling efficient Stille cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex nitrogen-containing heterocycles found in active pharmaceutical ingredients (APIs).
• Stille Cross-Coupling Reagent: Enables the coupling of the tetrahydropyridine moiety with aryl, vinyl, or heteroaryl halides/triflates to form new C-C bonds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Ligand & Catalyst Precursor: Serves as a precursor for the development of novel organometallic catalysts and ligands used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Useful for the site-specific modification of biomolecules or the synthesis of chemical probes for biological target identification.

Basic Information

Item	Details
Product Name	T-Butoxycarbonyl-4-Tributylstannyl-1,2,3,6-Tetrahydropyridine
CAS No.	208465-07-0
Molecular Formula	C22H43NO2Sn
Molecular Weight	472.29 g/mol
Synonyms	Boc-4-(Tributylstannyl)-1,2,3,6-tetrahydropyridine; 4-(Tributylstannyl)-1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(tributylstannyl)-3,6-dihydro-2H-pyridine-1-carboxylate; 1-Boc-4-(tributylstannyl)-1,2,3,6-tetrahydropyridine; N-Boc-4-(tributylstannyl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-(tributylstannyl)-1-pyridinecarboxylic acid 1,1-dimethylethyl ester; 208465-07-0; 4-Tributylstannyl-N-Boc-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our T-Butoxycarbonyl-4-Tributylstannyl-1,2,3,6-Tetrahydropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹⁹Sn), HPLC, and elemental analysis (Tin content), to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. The compound is moisture-sensitive and should be handled in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin Content (Analysis)	22.0 - 25.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.