Description

5-[[2,6-Difluoro-4-(trans-4-Propylcyclohexyl)Phenyl]Difluoromethoxy]-1,2,3-Trifluorobenzene is a high-purity, advanced fluorinated organic intermediate designed for sophisticated chemical synthesis. This compound matters for its role as a critical building block in the development of novel materials and active pharmaceutical ingredients, where its unique fluorinated aromatic and cyclohexyl structure imparts specific electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating next-generation products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Liquid Crystal Material Synthesis: Serves as a precursor for advanced fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Agrochemical Active Ingredient Development: Used in research to create new herbicides or pesticides with the fluorinated group potentially enhancing activity and environmental profile.
• Organic Electronics: Potential monomer or intermediate for synthesizing specialty polymers and small molecules used in OLEDs or organic semiconductors.
• Advanced Material Research: Employed in academic and industrial R&D to explore new fluorinated polymers or coatings with unique surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring complex fluorinated intermediates.

Basic Information

Product Name	5-[[2,6-Difluoro-4-(trans-4-Propylcyclohexyl)Phenyl]Difluoromethoxy]-1,2,3-Trifluorobenzene
CAS No.	208338-62-9
Molecular Formula	C22H21F7O
Molecular Weight	434.40 g/mol
Synonyms	1,2,3-Trifluoro-5-[[2,6-difluoro-4-(trans-4-propylcyclohexyl)phenyl]difluoromethoxy]benzene; 5-((2,6-Difluoro-4-(trans-4-propylcyclohexyl)phenyl)difluoromethoxy)-1,2,3-trifluorobenzene; 208338-62-9; Benzene, 1,2,3-trifluoro-5-[[2,6-difluoro-4-(trans-4-propylcyclohexyl)phenyl]difluoromethoxy]-; Difluoromethoxy-trifluorobenzene derivative; Fluorinated liquid crystal intermediate; trans-4-Propylcyclohexyl-based fluorobenzene.
EINECS	Contact for details

Quality Control

Our 5-[[2,6-Difluoro-4-(trans-4-Propylcyclohexyl)Phenyl]Difluoromethoxy]-1,2,3-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with your internal quality standards and research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.