Description

2,2-Dihydroxyacetic Acid (R)-(-)-Menthyl Ester is a high-purity chiral building block and flavor/fragrance intermediate. This compound matters for its role in synthesizing optically active molecules and for imparting unique organoleptic properties. It is needed by manufacturers in the pharmaceutical, flavor & fragrance (F&F), and fine chemical industries for applications requiring specific stereochemistry and high volatility.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the production of active pharmaceutical ingredients (APIs) where the (R)-(-)-menthyl moiety is used as a chiral auxiliary or resolving agent.
• Flavor and Fragrance Ingredient: Serves as a key component or precursor in creating sophisticated minty, cooling, or herbal notes in perfumes, cosmetics, and food flavorings.
• Asymmetric Catalyst Ligand Precursor: The chiral structure makes it a valuable starting material for synthesizing ligands used in asymmetric catalysis.
• Organic Synthesis Building Block: Employed in research and development for constructing complex natural products and specialty chemicals.
• Reference Standard for Analytical Testing: Used as a high-purity standard in GC, HPLC, or GC-MS for quality control in related chemical processes.

Basic Information

Item	Detail
Product Name	2,2-Dihydroxyacetic Acid (R)-(-)-Menthyl Ester
CAS No.	208192-14-7
Molecular Formula	C₁₂H₂₂O₄
Molecular Weight	230.30 g/mol
Synonyms	(R)-(-)-Menthyl Glyoxylate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate; (R)-Menthyl Dihydroxyacetate; Glyoxylic Acid (R)-(-)-Menthyl Ester; L-Menthyl Glyoxylate; (-)-Menthyl Glyoxylate; 2,2-Dihydroxyacetic Acid (-)-Menthyl Ester
EINECS	Contact for details

Quality Control

Our 2,2-Dihydroxyacetic Acid (R)-(-)-Menthyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including chiral purity (enantiomeric excess), chemical assay, and impurity profiling to ensure it meets the high standards required for pharmaceutical and flavor applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.