Description

1,3-Di-Boc-2-(Trifluoromethylsulfonyl)Guanidine is a highly specialized, protected guanidine derivative used as a key synthetic intermediate in advanced organic chemistry. Its core value lies in its dual role as a versatile guanidine protecting group and a reactive sulfonamide, enabling the controlled synthesis of complex nitrogen-containing molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing guanidine or amidine pharmacophores.
• Peptidomimetic Synthesis: Used to introduce protected guanidine functionalities that mimic the side chain of arginine in peptide analogs and protease inhibitors.
• Agrochemical Development: Serves as a precursor in creating new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Material Science Research: Employed in the development of specialty polymers, catalysts, and ligands where precise nitrogen functionality is required.
• Chemical Biology Probes: Facilitates the creation of labeled or modified guanidine compounds for studying biological recognition and enzyme mechanisms.

Basic Information

Product Name	1,3-Di-Boc-2-(Trifluoromethylsulfonyl)Guanidine
CAS No.	207857-15-6
Molecular Formula	C₁₃H₂₁F₃N₂O₆S
Molecular Weight	390.38 g/mol
Synonyms	1,3-Bis(tert-butoxycarbonyl)-2-[(trifluoromethyl)sulfonyl]guanidine; Di-Boc-triflylguanidine; N,N'-Di-Boc-N''-triflylguanidine; 1,3-Di-tert-butyl 2-(trifluoromethylsulfonyl)carbamimidate; Guanidine, N,N'-bis(1,1-dimethylethoxy)carbonyl-N''-[(trifluoromethyl)sulfonyl]-; BTTG; Boc-protected triflylguanidine
EINECS	Contact for details

Quality Control

Our 1,3-Di-Boc-2-(Trifluoromethylsulfonyl)Guanidine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.