Description

2-Fluoro-3-(trifluoromethyl)benzamide is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the benzamide core, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a building block for functional materials.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel fluorination methodologies.
• Advanced Material Precursor: Potential use in the synthesis of monomers for specialty polymers with tailored properties like chemical resistance and thermal stability.

Basic Information

Product Name	2-Fluoro-3-(trifluoromethyl)benzamide
CAS No.	207853-60-9
Molecular Formula	C8H5F4NO
Molecular Weight	207.13 g/mol
Synonyms	2-Fluoro-3-(trifluoromethyl)benzamide; Benzamide, 2-fluoro-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-2-fluorobenzamide; 2-Fluoro-alpha,alpha,α-trifluoro-m-toluamide; 207853-60-9; 2-Fluoro-3-trifluoromethylbenzamide; m-Toluamide, 2-fluoro-alpha,alpha,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(trifluoromethyl)benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.