Description

n-Alloc-1,5-Pentanediamine Hydrochloride is a protected diamine derivative, specifically the hydrochloride salt of 1,5-pentanediamine with an allyloxycarbonyl (Alloc) protecting group on the primary amine. This compound is a critical building block in advanced organic synthesis, particularly in peptide and medicinal chemistry, where it enables the controlled introduction of a diaminoalkane spacer. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for constructing complex molecules, linkers, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a flexible diamino linker.
• Peptide Chemistry: Used as a protected diamine building block for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Bioconjugation & Linker Synthesis: Integral for creating cleavable linkers in antibody-drug conjugates (ADCs) and other bioconjugation platforms.
• Polymer Science: Acts as a monomer or cross-linking agent for producing functionalized polyamides, polyurethanes, and dendrimers.
• Chemical Biology Probes: Employed in the development of molecular probes and tools where a protected, reactive amine handle is required.
• Material Science: Used in surface modification and the creation of amine-functionalized coatings and materials.

Basic Information

Product Name	n-Alloc-1,5-Pentanediamine Hydrochloride
CAS No.	207676-44-6
Molecular Formula	C9H19ClN2O2
Molecular Weight	222.71 g/mol
Synonyms	1,5-Pentanediamine, N-[(allyloxy)carbonyl]-, hydrochloride; N-Alloc-1,5-diaminopentane hydrochloride; N1-Alloc-cadaverine hydrochloride; 5-[(Allyloxycarbonyl)amino]pentylamine hydrochloride; Allyl (5-aminopentyl)carbamate hydrochloride; Alloc-Cadaverine·HCl; N-Alloc-pentane-1,5-diamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-Alloc-1,5-Pentanediamine Hydrochloride is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for research and cGMP manufacturing. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.