Description

3-Bromo-5-Fluoro-4-Methylaniline is a halogenated aniline derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for synthesizing fluorinated aromatic cores essential in electronic materials for displays and lighting due to its impact on molecular polarity and mesomorphic properties.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of high-performance polymers, including polyamides and polyimides, to improve thermal stability and chemical resistance.
• Dyestuff & Pigment Intermediate: Utilized in the manufacture of specialized azo dyes and organic pigments, where it contributes to color fastness and unique shade development.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl structures.

Basic Information

Product Name	3-Bromo-5-Fluoro-4-Methylaniline
CAS No.	207110-35-8
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	4-Amino-2-bromo-6-fluorotoluene; 2-Bromo-6-fluoro-4-aminotoluene; 4-Methyl-3-bromo-5-fluoroaniline; 3-Bromo-5-fluoro-p-toluidine; 3-Bromo-5-fluoro-4-methylbenzenamine; Benzenamine, 3-bromo-5-fluoro-4-methyl-; 5-Fluoro-3-bromo-4-methylaniline
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-4-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.