Description

4-(2,4,6-Trifluorophenyl)-3-Thiosemicarbazide is a specialized organic intermediate featuring a trifluorophenyl group linked to a thiosemicarbazide moiety, a structure of significant interest in advanced chemical synthesis. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine substitution pattern can enhance metabolic stability and bioavailability. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the thiosemicarbazide core is known for its biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the trifluoromethylphenyl group to improve product efficacy and environmental profile.
• Coordination Chemistry & Material Science: Serves as a versatile ligand for metal complexation, useful in creating catalysts or functional materials with specific electronic properties.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing more complex heterocyclic compounds, such as thiadiazoles and triazoles, via cyclization reactions.
• Analytical Reference Standard: Supplied as a high-purity standard for quality control and analytical method development in regulatory and research laboratories.

Basic Information

Product Name	4-(2,4,6-Trifluorophenyl)-3-Thiosemicarbazide
CAS No.	206761-92-4
Molecular Formula	C7H5F3N3S
Molecular Weight	228.20 g/mol
Synonyms	4-(2,4,6-Trifluorophenyl)thiosemicarbazide; 1-(2,4,6-Trifluorophenyl)thiosemicarbazide; 3-Thiosemicarbazide, 4-(2,4,6-trifluorophenyl)-; 2,4,6-Trifluorophenyl thiosemicarbazide; 4-(Perfluorophenyl)thiosemicarbazide (common name variant); TFP-thiosemicarbazide; N-(2,4,6-Trifluorophenyl)hydrazinecarbothioamide
EINECS	Contact for details

Quality Control

Our 4-(2,4,6-Trifluorophenyl)-3-Thiosemicarbazide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.