Description

4-(2,4-Difluorophenyl)-3-Thiosemicarbazide is a specialized organic intermediate featuring a difluorophenyl moiety linked to a thiosemicarbazide functional group. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients. The structural combination of fluorine atoms and the reactive thiosemicarbazide unit makes it a critical precursor for developing compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in antimicrobial, antiviral, and anticancer research programs.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the difluorophenyl group can improve lipophilicity and target binding.
• Chemical Synthesis: Serves as a precursor for heterocyclic compounds like thiadiazoles and triazoles, which are important scaffolds in medicinal and materials chemistry.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalytic applications or materials science due to its nitrogen and sulfur donor atoms.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	4-(2,4-Difluorophenyl)-3-Thiosemicarbazide
CAS No.	206559-58-2
Molecular Formula	C7H7F2N3S
Molecular Weight	203.21 g/mol
Synonyms	1-(2,4-Difluorophenyl)thiosemicarbazide; 2,4-Difluorophenyl thiosemicarbazide; 3-Thiosemicarbazido-2',4'-difluorobenzene; 4-(2,4-Difluorophenyl)thiosemicarbazide; N-(2,4-Difluorophenyl)hydrazinecarbothioamide; 2,4-Difluoro-1-thiosemicarbazidobenzene; (2,4-Difluorophenyl)thiosemicarbazide
EINECS	Contact for details

Quality Control

Our 4-(2,4-Difluorophenyl)-3-Thiosemicarbazide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.