Description

1-(2-Bromo-5-Trifluoromethylphenyl)-2-Thiourea is a specialized organic building block featuring a thiourea moiety linked to a halogenated and fluorinated aromatic ring. This unique structure makes it a valuable intermediate in advanced synthetic chemistry, particularly for constructing complex molecules with specific electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the thiourea group can act as a hydrogen-bond donor/acceptor.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity often associated with the trifluoromethyl and thiourea functional groups.
• Material Science: Acts as a monomer or cross-linking agent in the preparation of specialized polymers, resins, or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Synthesis: Functions as a versatile building block for creating libraries of compounds in medicinal chemistry for high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Utilized in the preparation of novel ligands for catalysis, where the thiourea moiety can coordinate to various metal centers.

Basic Information

Product Name	1-(2-Bromo-5-Trifluoromethylphenyl)-2-Thiourea
CAS No.	206559-47-9
Molecular Formula	C8H6BrF3N2S
Molecular Weight	299.11 g/mol
Synonyms	1-(2-Bromo-5-(trifluoromethyl)phenyl)thiourea; N-(2-Bromo-5-(trifluoromethyl)phenyl)thiourea; 2-Bromo-α,α,α-trifluoro-m-tolylthiourea; Thiourea, N-(2-bromo-5-(trifluoromethyl)phenyl)-; 1-(2-Bromo-5-trifluoromethyl-phenyl)-thiourea; (2-Bromo-5-trifluoromethylphenyl)thiourea
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-5-Trifluoromethylphenyl)-2-Thiourea is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.