Description

2,2-Dimethylpropanesulfonamide is a specialized sulfonamide derivative characterized by its unique sterically hindered structure. This compound serves as a valuable high-purity building block and key intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and material science sectors who require consistent quality and reliable supply for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a sterically hindered sulfonamide moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce sulfonamide functional groups into polymers, altering their solubility, thermal stability, or ionic properties.
• Organic Synthesis Reagent: Acts as a versatile reagent in nucleophilic substitution and condensation reactions to introduce the tert-butylsulfonamide group.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,2-Dimethylpropanesulfonamide
CAS No.	206066-14-0
Molecular Formula	C5H13NO2S
Molecular Weight	151.23 g/mol
Synonyms	tert-Butylsulfonamide; 2-Methyl-2-propanesulfonamide; tert-Butanesulfonamide; t-Bu-Sulfonamide; 2,2-Dimethyl-1-sulfamoylpropane; Pivalylsulfonamide; N-Sulfamoyl-2,2-dimethylpropaneamide; (tert-Butylsulfonyl)amine
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylpropanesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC, NMR, and Karl Fischer titration to ensure it meets exacting purity standards. Certificates of Analysis (COA) detailing all specification results are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.