Description

(E)-1-(2-Chloro-5-Thiazolylmethyl)-3-Methyl-2-Nitroguanidine is a high-purity, advanced chemical intermediate with a defined stereochemistry. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily required by R&D and production teams in the agrochemical and pharmaceutical industries for developing new active ingredients.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel neonicotinoid or other insecticide classes.
• Pharmaceutical Research: Serves as a specialized building block for medicinal chemistry programs targeting new therapeutic agents.
• Chemical Synthesis: Used in organic synthesis for the introduction of the nitroguanidine moiety into complex molecular architectures.
• Reference Standard: Supplied as an analytical standard for quality control and method development in manufacturing.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(E)-1-(2-Chloro-5-Thiazolylmethyl)-3-Methyl-2-Nitroguanidine
CAS No.	205510-53-8
Molecular Formula	C7H10ClN5O2S
Molecular Weight	263.71 g/mol
Synonyms	2-Nitro-1-((2-chloro-5-thiazolyl)methyl)guanidine; (E)-N-((6-Chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide (related isomer); Nitroguanidine derivative; Thiazole insecticide intermediate; 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine; 205510-53-8; (E)-Isomer of Chlorothiazolyl Nitroguanidine
EINECS	Contact for details

Quality Control

Our (E)-1-(2-Chloro-5-Thiazolylmethyl)-3-Methyl-2-Nitroguanidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.