Description

(2R,3S)-1-Carboxy-5-Iodo-4-Methyl-2,3-Dihydroxycyclohexa-4,6-Diene is a high-purity, stereochemically defined iodinated cyclohexadiene carboxylic acid derivative, serving as a critical chiral building block and synthetic intermediate. Its precise stereochemistry and reactive functional groups make it invaluable for constructing complex molecular architectures in advanced pharmaceutical research and fine chemical synthesis. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce complex, functionalized ring systems with high enantiomeric purity.
• Agrochemical Research: Intermediate in the synthesis of advanced crop protection agents and herbicides requiring specific stereochemistry for bioactivity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used in studying enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, specialty chemicals.
• Academic & Institutional Research: Used in universities and research institutes for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(2R,3S)-1-Carboxy-5-Iodo-4-Methyl-2,3-Dihydroxycyclohexa-4,6-Diene
CAS No.	205504-03-6
Molecular Formula	C9H9IO4
Molecular Weight	308.07 g/mol
Synonyms	5-Iodo-4-methyl-2,3-dihydroxycyclohexa-4,6-diene-1-carboxylic acid; (2R,3S)-5-Iodo-4-methyl-2,3-dihydroxy-1,4-cyclohexadiene-1-carboxylic Acid; (2R,3S)-1-Carboxy-5-iodo-4-methyl-2,3-dihydroxy-1,4-cyclohexadiene; Iodinated Dihydroxy Methyl Cyclohexadiene Carboxylic Acid; Chiral Iodocyclohexadiene Derivative; CAS 205504-03-6
EINECS	Contact for details

Quality Control

Our (2R,3S)-1-Carboxy-5-Iodo-4-Methyl-2,3-Dihydroxycyclohexa-4,6-Diene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.